Services
The study and development of anti-angiogenic therapies depends on reliable and reproducible stimulation models of neovascular response.
Corneal Micropocket Assay
Piedmont Research Center has several experimental techniques that allow us to achieve an effective examination of short-term neovascularization and angiogenic response to the desired ligand (BfGf, VEGf).
- Hydron pellet preparation with varying growth factors chosen for specific study requirements.
- Surgical techniques, where trained veterinary surgeons implant the pellet into the base of the corneal micropocket
- Histologic examination records neovascularization in the cornea using a slit-lamp microscope connected to a camera
As with other angiogenesis models, the corneal micropocket assay has the following advantages:
- Reproducible
- Readily documented
- Economical
- Rapid turnaround times
Our study reports are then customized to meet a client's needs and may include basic study data including photographs, review of methods and evaluation of results.
