Bioavailability and acute toxicology evaluation are critical components of early preclinical drug development.
Acute Toxicity & Pharmacokinetics
Piedmont Research Center offers basic services in bioavailability, pharmacokinetics and toxicity analysis. All studies are conducted in the spirit of good laboratory practice (GLP).
Toxicology studies can include any or all of the following:
- Timed dosing and sampling
- Tissue and/or organ preservation
- Plasma and/or serum sampling
- Radiolabeled compounds
- Histology and pathology
- CBC with differentials
- Chem CS
- GLP monitoring
Pharmacokinetic sampling can be designed as a stand-alone, one- to 30-day study, or it can be incorporated into a client's efficacy protocol.
PCNA - mouse duodenum
BrdU mouse duodenum